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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08
filingDate 2007-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56eb57afed2c69fb0a12353294162a1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc5870d11ee34ef39a590bf82db19ec8
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publicationDate 2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2668650-C
titleOfInvention Crosslinked hyaluronic acid and its process of preparation
abstract The invention relates to a cross-linked hyaluronic acid that can be produced by a method comprising: (a) activating a hyaluronic acid; (b) reacting the activated hyaluronic acid with a cross-linking agent containing an oligo- or polypeptide in a reaction medium at a pH of between 8 and 12 in order to obtain a cross-linked hyaluronic acid; (c) adjusting the pH of the reaction medium to a value between 5 and 7; and (d) precipitating the cross-linked hyaluronic acid in an organic solvent. The invention also relates to the above method, to a hydrogel obtained from said cross-linked hyaluronic acid, and to the use of the cross-linked hyaluronic acid for the production of implants that can essentially be used in plastic surgery.
priorityDate 2006-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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