http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2667957-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 |
| filingDate | 2007-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94e08ee82be7ab983b91a5fd69c4ae14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02617c9656e5b6d4fe00fa5a6bffecc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b98d4c29f68b44ab640dc7e79c07a7c6 |
| publicationDate | 2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2667957-C |
| titleOfInvention | Methods and apparatuses for electrochemical determination of factor xa inhibitors in blood samples |
| abstract | The invention concerns methods and devices for determining factor Xa inhibitors in particular heparins and fractionated or low-molecular-weight heparins as well as direct factor Xa inhibitors in blood samples which are characterized in that in a first step the blood sample is brought into contact with a detection reagent which contains at least one thrombin substrate which consists of a peptide residue that can be cleaved by thrombin and is amidically bound via the carboxyl end to an electrogenic substance, and with a known amount of factor X reagent and an activator reagent which induces the conversion of factor X into factor Xa, subsequently in a second step the amount or activity of the electrogenic substance which is cleaved from the thrombin substrate by the factor Xa-mediated thrombin activation and/or the time course thereof is determined as the measurement signal using electrochemical methods, and finally in a third step the amount of the factor Xa inhibitor in the sample of the blood to be analysed or a measured quantity that correlates therewith, in particular a clotting time that correlates therewith, is determined on the basis of this measurement signal. |
| priorityDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.