abstract |
The invention relates to phenylpropionamide compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A, B, R1, R2, R3, R4 and R5 are defined as set forth in the specification. T he invention is also directed to the use of compounds of Formula (I) to trea t, prevent or ameliorate a disorder responsive to the activation of opioid r eceptors, particularly .mu.-opioid receptors. Compounds of the present inven tion are especially useful for treating pain. |