abstract |
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) ant igen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutr alizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that com pete for binding with the IL-17RA neutralizing antibodies described herein.< /SDOAB> |