| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_681ff6871f0118f0ac26adb6337c6bec |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C259-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
| filingDate |
2007-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1480800657b718bdc36374a8a78866a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_390693cf07bd9a2132582962d5f6e7ae |
| publicationDate |
2008-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2660163-A1 |
| titleOfInvention |
Potentiation of antifungal compounds |
| abstract |
The invention provides methods and models for understanding how HDAC inhibitors interact with antifungal azole compounds to potentiate the activity of such compounds, using fungal strains which have selective knockouts of fungal HDAC genes. The invention further provides methods for testing antifungal agents for potential synergy with fungal HDAC inhibitors, and thus provides antifungal compound which are identified according to the methods of the invention, and methods for treatment of fungal infections using such compounds. |
| priorityDate |
2006-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |