http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2654126-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132aa5ddba376cda52c2bedb26765245 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-36 |
| filingDate | 2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd07d89ae6002a77f4c22826ae4ec9cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_785c6c1b8ea3dece7a3e2db2d2b21ecd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_191ed271ad9c730b08538365d8938c73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c32c2556cb5972ea0c04bfb3b88eda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ebf93bca6439c296dced50e3e86d06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d8dfdbfb7fa83bb75bd5a2a0d2ca8f6 |
| publicationDate | 2007-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2654126-A1 |
| titleOfInvention | Crystalline forms of 11.beta.-(4-acetylphenyl)-20,20,21,21,21-pentafluoro-17-hydroxy-19-nor-17.alpha.-pregna-4,9-dien-3-one |
| abstract | The present invention relates to crystalline forms of 11 ß-(4-acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17.alpha.-pregna-4,9-dien-3-one. In particular, the invention relates to two crystalline ansolvate/anhydrate forms of this compound, polymorphs I and II. However, the present invention also relates to crystalline solvates, for example, methanol and ethanol solvates of 11 ß-(4-acetylphenyl)- 20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17.alpha.-pregna-4,9-dien-3-one, as precursors for the preparation of these two polymorphs I and II. Processes are described for the preparation of polymorph I by means of displacement crystallization or by means of extraction. The choice of the last solvent, before the ansolvate formation can take place, on the basis of the differences in the purification ratios of the individual solvates of 11 ß-(4-acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17.alpha.-pregna-4,9-dien-3-one is described. Polymorph I, according to the invention, is particularly suitable for the preparation of drugs. |
| priorityDate | 2006-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.