abstract |
A crystalline form of 5(S)-(2'-hydroxyethoxy)-20(S)-camptothecin diastereoisomer of 5(RS)-(2'-hydroxyethoxy)-20(S)-camptothecin is described that is characterized by having an X-ray powder diffraction pattern comprising one or more peak intensities expressed in degrees 2.theta. that are selected from the group consisting of 7.2 ± 0.1, 9.4 ± 0.1, 11.02 ± 0.1, 12.00 ± 0.1, 14.54 ± 0.1, 15.2 ± 0.1, 18.92 ± 0.1, 21.86 ± 0.1, 22.74 ± 0.1 and 26.42 ± 0.1. Methods of making and using the compound are also described. |