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filingDate 2007-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcba971278fa9ba61223482d5e5a6e80
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publicationDate 2008-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2653295-A1
titleOfInvention Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof
abstract Disclosed are: a safe bio-degradable/absorbable polymer having an extremely low metal catalyst content while retaining properties desired for a medical implant; a process for the production of the polymer; and a method for reducing the content of a metal catalyst in a bio-degradable/absorbable polymer, which can be applied on an industrial scale. Specifically, disclosed is a process for the production of a bio-degradable/absorbable polymer having a content of a metal catalyst of less than 1 ppm in terms of a metal, comprising the following steps (1) and (2): (1) copolymerizing lactide and .epsilon.-caprolactone at a molar ratio ranging from 40/60 to 60/40 in the presence of a metal catalyst to produce a copolymer; and (2) washing the copolymer with a mixed solvent comprising acetic acid and isopropanol at a ratio ranging from 25/75 to 45/55 by volume at a temperature lower than 40~C, and then drying the copolymer. Also specifically disclosed is a process for the production of a bio-degradable/absorbable polymer having a content of a metal catalyst of less than 1 ppm in terms of a metal, comprising the following steps (1) and (2): (1) copolymerizing lactide and .epsilon.-caprolactone at a molar ratio ranging from 65/35 to 85/15 in the presence of a metal catalyst to produce a copolymer; and (2) washing the copolymer with a mixed solvent comprising acetic acid and isopropanol at a ratio ranging from 45/55 to 55/45 by volume at a temperature lower than 40~C, and then drying the copolymer.
priorityDate 2006-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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