http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2653104-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efbd7e26e2299a71a466221ae638c641 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-99001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01087 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate | 2007-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16561728d14c15811ee8d5e39826dd7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93f2911b61dc37007e2c9ad68ff18b84 |
| publicationDate | 2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2653104-A1 |
| titleOfInvention | Preparation and uses of gene sequences encoding chimerical glycosyltransferases with optimized glycosylation activity |
| abstract | The present invention relates to the production of gene sequences encoding chimerical membrane glycosyltransferases presenting an optimized glycosylat ion activity in cells transformed with said sequences, said gene sequences corresponding to the fusion : of a first nucleic acid coding for a C-terminal minimal fragment of the catalytic domain (CD) of the native full length glycosyltransferase, to a second nucleic acid coding for a transmembrane peptide comprising in its N-terminal region a cytoplasmic tail (CT) region located upstream fro m a transmembrane domain (TMD), itself located upstream of a stem region (SR), provided that at least one of these CT, TMD, SR peptides being different from the primary structure of the naturally occurring peptide counterparts present in the native glycosyltransferase from which is derived the CD fragment with optimal glycosyltransferase activity as defined above. The invention also relates to the use of said gene sequences in the frame of the preparation of recombinant proteins of interest by cells transformed with said sequences and sequences encoding said recombinant proteins. |
| priorityDate | 2006-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 489.