| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65583
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-02 |
| filingDate |
2007-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_def54360ed800244b57e6ba0036985b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd5c6fa62e5a84b065495d0178e7637b |
| publicationDate |
2014-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2650518-C |
| titleOfInvention |
Process for the preparation of pyrazolylaminoquinazoline derivatives comprising a phosphate group |
| abstract |
The invention relates to a new process useful in the preparation of pharmaceutical compounds such as 2- (ethyl[3-({4-[(5- (2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl]amino}ethyldihydrogen phosphate (AZD1152): (See above formula) and intermediates used therein of formula (IIA): (See formula IIA) wherein R is an acid labile protecting group, e.g. tert-butyl, trityl, p-methoxyphenyl, benzyl or phenyl. |
| priorityDate |
2006-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |