| abstract |
It is intended to provide a compound which has an ACC inhibitory effect, is useful in preventing and treating obesity, diabetes, hypertension and so on and has excellent characteristics in drug effect, duration of the action, specificity, low toxicity and so on. Namely, a compound represented by the following general formula or a salt thereof: (I) wherein the ring M represents a 5- or 6-membered aromatic ring; W represents C or N; K represents a methylene group, an imino group, etc.; R represents a hydrogen atom, a hydrocarbon group, etc.; T and U independently represent each a hydrogen atom or a substituent, or T and U form together with the ring M an optionally substituted bicyclic ring; D and G independently represent each a carbonyl group or a sulfonyl group; the ring P represents optionally substituted piperidine, etc.; B represents CH or N; the ring Q represents an optionally substituted monocyclic ring; A represents C, CH or N; and J represents a hydrocarbon group, etc., provided that when the moiety W in the ring M is =N- or ~N=, U is nil. |