http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2646667-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a084f722795b1d4d4932a6f3a4e63cb8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06 |
| filingDate | 2007-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e0e7a57f05b664e04750d48c5fa670 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cbdd8bed4045bede89f3271007969d8 |
| publicationDate | 2007-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2646667-A1 |
| titleOfInvention | Methods of treating hot flashes with formulations for transdermal or transmucosal application |
| abstract | The present invention relates to transdermal or transmucosal formulations, methods of use for preparing medicaments for treating hot flashes and methods for treatment thereof by administering such formulations for transdermal or transmucosal administration of estrogen. The formulations are effective at surprisingly low daily doses, preferably the lowest effective dose of estrogen to treat hot flashes, namely about 0.45 to about 0.6 mg of estrogen per day in a delivery vehicle that includes a C2 to C4 alkanol, a polyalcohol, and a permeation enhancer of monoalkyl ether of diethylene glycol. The amount of estrogen which is administered produces an estimated nominal daily estrogen dose in a subject undergoing treatment of from about 10 to about 15 micrograms, and a serum estradiol level of between about 25 pg/ml to about 50 pg/ml. |
| priorityDate | 2006-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.