| abstract |
Compounds of formula I (see formula I) wherein R1, R2, R4 and R5 are independently from each other hydrogen, C1-C6alkyl, C1-C6alkoxy or halogen; R3 is C1-C6alkyl, C1-C6alkoxy, aryloxy, C3-C7cycloalkyl or pentafluorosulphuranyl; R6 is hydrogen or C1-C6alkyl; R7 is hydrogen, C1-C6alkyl, hydroxy or halogen; R8 is phenyl which is unsubstituted or substituted by one or two groups independently selected from halogen, C1-C6alkyl, halogen-C1-C6alkyl and halogen-C1-C6alkoxy; R9 is 1H-pyrrolo[2,3-c]pyridin-7-yl, 1H-pyrazolo[3,4-c]pyridin-7-yl or (see above formula) wherein R17 and R18 are independently hydrogen, halogen, C1-C6alkyl, halogen-C1-C6alkyl or C(O)OCH3, and X is =CH- or =N-; n is 1, 2 or 3; and pharmaceutically acceptable salts thereof Also described are processes for preparation of the compounds, their use as pharmaceuticals, and pharmaceutical compositions comprising them. |