http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2637879-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66c1b22707b0276e3078713a6ddcba91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
filingDate | 2007-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_961cfdfd29d267010df60bae50e5d435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20bdd567bfb15b1cd1c1eb0084ac89de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_967fc62f1b9b03e1a9aee44b4fb3efc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8501c11f269a6071b2e528192376d4d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3affc25ed981a4e703946dbb5bb0f541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94adb7aa4c8d8d47e4a78f19a09f0242 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_005b006d4f46db8159a0868b8ea967d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc78f720c925d213b300d8bc2ab4af2 |
publicationDate | 2007-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2637879-A1 |
titleOfInvention | Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection |
abstract | The present invention provides nucleoside aryl phosphoramidates of structural formula (I) which are precursors to inhibitors of RNA-dependent RNA viral polymerase. These compounds are precursors to inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as precursors to inhibitors of hepatitis C virus (HCV) NS5B polymerase, as precursors to inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside aryl phosphoramidates alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the nucleoside aryl phosphoramidates of the present invention. |
priorityDate | 2006-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 445.