abstract |
The present invention relates to sugar-derived compounds that mimic Shigella flexneri serotype 3a and X epitopes and their use for the preparation of vaccine compositions. The present invention also relates to novel glycoconjugate compounds comprising oligo- or polysaccharides described hereinafter, to the process for the synthesis of these oligo- or polysaccharides and glycoconjugates, to derivatives of these oligo- or polysaccharides, to compositions containing them. , as well as the use of glycoconjugates for vaccination purposes. The present invention also provides methods for diagnosing Shigella flexneri infection using one or more oligo- or polysaccharides or their conjugates. |