| abstract |
In its many embodiments, the present invention provides a novel class of amino-substituted pyrazolo[l , 5 -a] pyrimidine compounds represented by the structural formula (I) as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of preparing pharmaceutical formulations including one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the protein or checkpoint kinases using such compounds or pharmaceutical compositions. |