Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 |
filingDate |
2006-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98f12c8b65724f1e3c9e05875f98473c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26a58099ba34131114c0556fba8d6af6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8adf54e85471c216497c7e8d9a827a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f37f3e648754a98df363d77e1cbd14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61f19ee36da53c765ef93bc0746da6dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dc20ee6e4315a4cd18be6fc95d65068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2a6cbfefd2671d8725c5e8fc062f4d |
publicationDate |
2007-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2619641-A1 |
titleOfInvention |
Systemic and intrathecal effects of a novel series of phospholipase a2 inhibitors on hyperalgesia and spinal pge2 release |
abstract |
Phospholipase A2 (PLA2) forins are expressed in spinal cord whose inhibition induces a potent antihyperalgesia. PLA2 inhibitor compounds are provided that include a common motif consisting of a 2-oxoamide with a hydrocarbon tail and a four carbon tether. The compounds block Group IVA calcium dependent PLA2 (cPLA2) and/or Group VIA calcium independent PLA2 (iPLA2) and/or Group V secreted PLA2 (sPLA2). |
priorityDate |
2005-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |