Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6420d04b0d68f339771080e32bd0fbc9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2006-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7eaaf18fec82662a8ee32f7ce263f72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f01d27d666695f1b99bae5f6e3808d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43d4b4182bb63cff47a7fa0c18fdac99 |
publicationDate |
2007-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2618508-A1 |
titleOfInvention |
Truncated memapsin 2 for use for treating alzheimer's disease |
abstract |
The present invention provides novel methods of reducing memapsin 2 .beta.-secretase activity in a subject, decreasing levels of .beta.-amyloid peptide in the brain of a subject, treating Alzheimer's disease and/or reducing the size and/or number of .beta.-amyloid plaques in the brain of a subject. The methods may include the step of administering an effective amount of truncated memapsin 2 protein, anti-truncated memapsin 2 antibody, and/or nucleic acid encoding a truncated memapsin 2 protein or anti-truncated memapsin 2 antibody. The present invention also provides related pharmaceutical compositions and uses thereof. |
priorityDate |
2005-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |