http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2617832-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee1c19da359446fb5c4f0458a57b783d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 2006-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db872a903f9f344046ceb258d55165a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af95b2b449be2907e49c861cdc50fad4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_711d90023e925a32b51c23969b0c3345 |
| publicationDate | 2007-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2617832-A1 |
| titleOfInvention | Yeast host, transformant and method for producing heterologous proteins |
| abstract | It is intended to elevate the efficiency of producing a foreign protein in a transformant with the use of a yeast as a host. A method of constructing a host for expressing a foreign gene wherein one or more genes selected from the group consisting of protease-associated genes (in particular, metalloprotease-associated genes and serine protease-associated genes) of Schizosaccharomyces pombe are deleted or inactivated; a host from which the above-described gene(s) have been deleted or inactivated; a transformant constructed by transferring a foreign gene into the above host; and a method of producing a foreign protein by using the above transformant. It is preferred that the protease-associated gene(s) are one or more genes selected from the group consisting of psp3(SPAC1006.01), sxa2(SPAC1296.03c), ppp51(SPAC22G7.01c) and ppp52(SPBC18A7.01) or two or more genes selected from the group consisting of metalloprotease-associated genes and serine protease-associated genes. A particularly preferable host is one from which at least three genes including psp3(SPAC1006.01), isp6(SPAC4A8.04) and ppp53(SPAP14E8.04) have been deleted or inactivated. A still preferable host is one from which four genes including ppp16(SPBC1711.12) in addition to the three genes as cited above,or five genes including ppp22(SPBC14C8.03) in addition to the four genes as cited above have been deleted or inactivated. |
| priorityDate | 2005-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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