| abstract |
The present invention relates to compounds of formula (I) wherein R1 is hydrogen, halogen or lower alkyl; R2 is lower alkyl or cycloalkyl; R3 is hydrogen, lower alkyl, lower alkyl substituted by halogen, cycloalkyl or is benzyl, optionally substituted by halogen; n is 0, 1 or 2; and pharmaceutically acceptable acid addition salts thereof. The compounds of formula (I) may be used for the treatment of 5-HT5A receptor antagonists related diseases, which are depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, disorders of eating behaviors, sexual dysfunction, sleep disorders, withdrawal from abuse of drugs, motor disorders such as Parkinson's disease, dementia in Parkinson's disease, neuroleptic-induced Parkinsonism and tardive dyskinesias, as well as other psychiatric disorders and gastrointestinal disorders such as irritable bowel syndrome. |