Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9720f40c8c2df78174f19715e6882378 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-332 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-15 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate |
2006-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36230951c771f6404b2977a41ed812ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7226555ea3b8959635b6fa795cf55247 |
publicationDate |
2015-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2609365-C |
titleOfInvention |
Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (tina) and process for the preparation of tina |
abstract |
The present invention describes a flexible basestacking monomer that can be incorporated into an oligonucleotide or oligonucleotide analogue, as well as triplex forming oligonucleotides comprising the flexible basestacking monomer. Triplex forming oligonucleotides of the invention are capable of binding sequence specifically to doublestranded target nucleic acids and are therefore of interest for modulation of the activity of target nucleic acids and also detection of target nucleic acids. |
priorityDate |
2005-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |