http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2606906-A1

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filingDate 2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23270e8b7f2b97e3bc95e33b8d9eb19d
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publicationDate 2006-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2606906-A1
titleOfInvention Fluorogenic measurment of thrombin activity in a thin layer of whole blood
abstract The invention relates to a method for in vitro determining thrombin activity in a sample wherein the sample is a blood sample and thrombin generation is measured by the steps of: - contacting a layer of said sample with a fluorogenic substrate of thrombin, wherein said layer has a thickness within a range of 0.05 to 5 mm and a surface within a range of 10 to 500 mm2; -allowing thrombin to generate in said sample; - measuring the fluorescence emitted from the surface of the layer, by the fluorescent group released from the fluorogenic substrate as a result of enzymatic action of generated thrombin on said fluorogenic substrate.
priorityDate 2005-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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