| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
| filingDate |
2005-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7fe4d1c3fd32b8fac0dbfef35c93b85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c24e5cb3392b606cf704ba29aa21aae5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a76939d506bed448120177de04ac2641
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66d152635d85cc84fe8b161ab8ca5710
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e50d88bbe7fac0d5f7b431087b637f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ba7b5326f901f004962f6901cef93aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c729e1231ed3c0578c5a28f2917085a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8437a4ac43e70872f7bd00075d27bb14 |
| publicationDate |
2009-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2590735-C |
| titleOfInvention |
Process for the preparation of 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl) ethoxy}-5-tetrahydropyran-4-yloxyquinazoline, their intermediates and crystalline salts thereof |
| abstract |
The present invention relates to chemical processes useful in the manufacture of the compound 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]- 5-tetrahydropyran-4-yloxyquinazoline (the active entity within AZD0530), to intermediates useful in the manufacture of that compound and to processes for the manufacture of those intermediates. The invention also relates to particular crystalline forms of that compound such as a difumarate salt and a trihydrate and to pharmaceutical compositions containing such crystalline forms. |
| priorityDate |
2004-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |