http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2585271-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630f924c1eea9d4921e893ad6c349c9b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-324 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2005-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56bb0f15ca3723fcfeae90ce6cde7189 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67c3c79bbdbf1a06140915fb9b8d6f59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38306b217ed6a816166024e8831e920e |
publicationDate | 2012-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2585271-C |
titleOfInvention | Plgf and sflt-1 as prognostic parameters for cardiovascular diseases |
abstract | The present invention refers to a use of an ex vivo method comprising the determination of P1GF and sFlt-1 in a sample for diagnosis, risk stratification and/or monitoring of a vascular disease with atherosclerotic etiology, in particular a coronary heart disease such a unstable angina pectoris or myocardial infarction, and/or for estimation of the probability of developing such a disease, as well as for identification of a patient supposed to benefit from a therapy by agents reducing the risk for a cardiovascular disease. In the method (i) a ratio of [P1GF = high : sFlt-1 = low], and/or (ii) a P1GF concentration in the upper two tertiles of a reference collective, and an sFlt-1 concentration in the lower tertile of the reference collective, and/or (iii) a P1GF result above a P1GF reference value, and an sFlt-1 result below an sFlt-1-reference value indicate an elevated probability for an adverse event. The present invention also refers to the used method. The present invention further refers to a diagnostic kit and its use as well as to an assay element and its use. |
priorityDate | 2004-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 2129.