| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-84 |
| filingDate |
2005-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f3254c23b7593aecebfcfade1d11117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_602bbbbd65a25d1d872d56c1af8f808d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2198beba502a5f0d1355299a322e6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b96ba7eba67eff849cd05edcbff809f |
| publicationDate |
2012-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2580973-C |
| titleOfInvention |
Intermediate of 6-substituted 1-methyl-1-h-benzimidazole derivative and method for producing same |
| abstract |
The object of the present invention is to provide new intermediates (IIa) and (III) of the 6-substituted-1-methyl-1-H-benzimidazol derivatives (I) which are publicly known pharmaceutically active ingredients, and a preparation procedure suitable for a large scale synthesis of N-(5-substituted-2-nitrophenyl)-N-methylamines (II) which are synthetic intermediates. Additionally, another object of the present invention is to provide an efficient procedure for the preparation of the 6-substituted-1-methyl-1-H-benzimidazole derivative (I) from said synthetic intermediates (II) in a shorter number of steps. [Measures to solve the subject] The present invention relates to a procedure for the preparation of a compound (I) represented by the following formula and synthetic intermediates of said compound (I). (see formula III) (see formula I) (In the above reaction scheme, R2 represents a phenyl group which may optionally be substituted with substituents such as a C1-C6 alkyl group or the like, and X represents an oxygen atom, a sulfur atom or a nitrogen atom). |
| priorityDate |
2004-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |