| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C219-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C219-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-421
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- |
| filingDate |
1996-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e87ddcfb69ffc8d8051be322bbe0a1ab |
| publicationDate |
1997-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2572508-A1 |
| titleOfInvention |
One pot synthesis of 2-oxazolidinone derivatives |
| abstract |
The present invention provides an improved process for preparing (S)-4-{[3-[2-(dimethylamino)ethyl)-1H-indol-5-yl]methyl}-2-oxazolidinone which comprises: a) forming a carbamate of formula (III), from methyl 4-nitro-(L)-phenylalaninate hydrochloride; b) reducing the compound of formula (III) to give the compound of formula (IV); c) reducing the methyl ester grouping in the compound of formula (IV) to give the compound of formula (V); d) ring closure of the compound of formula (V) to give the compound of formula (VI); e) diazonium salt formation from the compound of formula (VI) followed by reduction to give the compound of formula (VII); f) Fischer reaction of the compound of formula (VII) to give (S)-4-{[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl)-2-oxazolidinone. |
| priorityDate |
1995-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |