http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2571323-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2901e694724c2a759f619944cb7d2a4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2005-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16b16344dc25b37a681285397c1515bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d32c081b97df6443b131e4d16174e2c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce8d33f602ee0e405b41dbaaf3a207a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1374dad2a8566e56ff68398bffe97fa7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7ddccb92263833e472bf9cb74b83b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf60954b39d931adb1a741f3f040b06f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48e15bfb87e8a5aaf6a718b538068e12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fed3385db34ff92388add0406f94143d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d5f0e02488f9442e660e31d020ee1b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d300a4040f7b1e89d59cddcc4b3db46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c77f465c0d490d6aea6f2fd6225c9631 |
| publicationDate | 2006-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2571323-A1 |
| titleOfInvention | Novel cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors |
| abstract | The invention relates to products of formula (I): in which p = 0, 1 and 2; A = aryl, heteroaryl, carbocycle or heterocycle; X = single bond; -N(R6)-; -NH-alk-; alkylene; -O-; -C(O)-; -S(O)n-; -N(R6)-C(O)-; -NH-CO-alk-, -N(R6)-C(O)-N(R6')-; -N(R6)-C(S)-N(R6')-; -N(R6)-C(O)O-; -N(R6)-SO2-; -N(R6)-SO2-N(R6')-; -C(O)-N(R6)-; -SO2-NR6-; and -C(O)O-; L1 = single bond, alkylene, alkenylene, alkynylene, cycloalkylene, phenylene, heteroarylene; all optionally substituted; R1 = hydrogen, alkyl, alkenyl, alkynyl or cycloalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl; -SO2R9, -C(O)R9; -C(O)OR9,-C(O)NR10R11, -C(S)NR10R11,-SO2NR10R11; R2 = hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, either R1 and R2 with N, or NR1R2 with L1 may form a saturated or unsaturated heterocycle possibly containing O, N, S; R3 = hydrogen; halogen; alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylenedioxy, heterocycle, aryl and heteroaryl, all optionally substituted; S(O)n-alkyl; amino, alkylamino, dialkylamino, with dialkylamino optionally forming with N a cycle, all optionally substituted; R4, R4' and R4''= hydrogen, halogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, oxo; with two from among R4, R4' and R4'' possibly forming with C a ring possibly containing O, N or S; L2 = single bond, alkylene, alkenylene, alkynylene, cycloalkylene, -O-, -NR17-, -C(O)-, SO2; Y = N-heterocycle possibly containing O, N or S; R5 = hydrogen, halogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl; all these radicals being optionally substituted, these products being in all the isomeric forms and the salts, as medicinal products. |
| priorityDate | 2004-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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