http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2568504-A1
Outgoing Links
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|---|---|
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| filingDate | 2006-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5e6fe35953c78069e1b3c40daf56d6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46f83a23276ac294c4d9bc443c054bdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_306a212ff074458afe717a5b3d5e167d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07ede08b558d88ee674a63289aee19ed |
| publicationDate | 2007-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2568504-A1 |
| titleOfInvention | Local vascular delivery of p13 kinase inhibitors alone or in combination with sirolimus to prevent restinosis following vascular injury |
| abstract | Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices. |
| priorityDate | 2005-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 634.