| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33e0cb77260827966a920f9232dfb4f9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 |
| filingDate |
2005-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a8f90cb153e8f39d9464b4f1c0eec2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a4c6a1e71ce19aa73e18f5c406299ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cd6e5943e9d2af3685c55afa5b99ba3 |
| publicationDate |
2005-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2565115-A1 |
| titleOfInvention |
Methods for stem cell expansion and differentiation |
| abstract |
The present invention provides methods, culture media, and apparatus to produce useful amounts of specific cell populations ex vivo by the modulation of Opn and/or an active Opn fragment. The present invention provides ex vivoexpanded populations of HSC for use in transplantation therapy and in clinical and research activities, such as drug screening, toxicity testing, and other research activities. Also provided are methods, devices and culture media are provided to inhibit Opn binding to HISC to promote the increased production of more differentiated cell populations. |
| priorityDate |
2004-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |