http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2558908-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea17ba87480b776cce77451f86b25bb |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 |
filingDate | 1996-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94b42183691f6f4e02ad6fbd2cb5a3fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1a5cb22ab6995f3d42ff93eb5b3629d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd1ce7105a4dfaa7b96678fa505beda |
publicationDate | 2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2558908-C |
titleOfInvention | 10-deacetylbaccatine iii and 10-deacetyl 14.beta.-hydroxybaccatine iii derivatives and intermediates useful in the preparation thereof |
abstract | The present invention is directed to intermediates useful in the preparation of novel derivatives of 10-deacetylbaccatine III and of 10-deacetyl-14.beta.-hydroxybaccatine III. These novel derivatives have cytoxic and anti-tumoral activity. They are prepared starting from the so-called syntons or from other taxanes of natural origin, by selective oxidation of the hydroxyl in position 10 to keto function and subsequent esterfication in position 13, if necessary, with isoserine chains variously substituted. The products of the invention can be administered by injection or orally, when suitably formulated. |
priorityDate | 1995-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.