http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2558908-C

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Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea17ba87480b776cce77451f86b25bb
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337
filingDate 1996-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94b42183691f6f4e02ad6fbd2cb5a3fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1a5cb22ab6995f3d42ff93eb5b3629d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fd1ce7105a4dfaa7b96678fa505beda
publicationDate 2009-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2558908-C
titleOfInvention 10-deacetylbaccatine iii and 10-deacetyl 14.beta.-hydroxybaccatine iii derivatives and intermediates useful in the preparation thereof
abstract The present invention is directed to intermediates useful in the preparation of novel derivatives of 10-deacetylbaccatine III and of 10-deacetyl-14.beta.-hydroxybaccatine III. These novel derivatives have cytoxic and anti-tumoral activity. They are prepared starting from the so-called syntons or from other taxanes of natural origin, by selective oxidation of the hydroxyl in position 10 to keto function and subsequent esterfication in position 13, if necessary, with isoserine chains variously substituted. The products of the invention can be administered by injection or orally, when suitably formulated.
priorityDate 1995-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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