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filingDate 2004-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17c8b2eff82255e5f8ec69543c59e4e
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publicationDate 2014-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2557612-C
titleOfInvention Methods, peptides and biosensors useful for detecting a broad spectrum of bacteria
abstract Described herein are methods of detecting a wound infection and for detecting the presence or absence of bacteria, for example, wound bacteria in a sample, by contacting a sample with a peptide substrate derived from the modification of the reactive site loop (RSL) domain of the .alpha. l- proteinase inhibitor. In the current invention, we have demonstrated that these peptide substrates without the alpha 1 protein can be efficiently used as peptide substrates. The modification or the absence of modification of this peptide substrate by the enzyme produced and/or secreted by the bacteria, can serve as an indicator for the presence or absence of the bacteria in the sample. The present invention also features a biosensor for detecting the presence or absence of bacteria in a sample.
priorityDate 2003-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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