Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate |
2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f55f7bf6085eda28f226059a9d3c9b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00b7a9d73faef3fb7e1d08041dddeefd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ba0ad9351cebc067eb9bc78e9943892 |
publicationDate |
2005-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2556594-A1 |
titleOfInvention |
3'-end nucleoside unit comprising phosphoramidite |
abstract |
It is intended to provide a method of binding a 3~-terminal nucleoside to a hydroxyl group on a solid phase under the same conditions as in a DNA chain extension reaction. A 3~-terminal nucleoside unit containing phosphoramidite which is a compound represented by the following general formula (I): (N)-O-(R1)Si(R2)-(C6H4)-(CH2)n-O-P(OR3)N(R4)(R5) wherein (N) stands for an arbitrary nucleoside or its derivative; R1, R2, R4 and R5 are each an alkyl group or an aryl group; R3 is a phosphate-protecting group; and n is an integer of from 1 to 5; a solid phase support having a 3~-terminal nucleoside unit, which is the above compound, transferred thereinto; and a method of synthesizing a nucleic acid oligomer with the use of this solid phase support. |
priorityDate |
2004-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |