| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-173
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-073 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-173
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ba0ad9351cebc067eb9bc78e9943892
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f55f7bf6085eda28f226059a9d3c9b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00b7a9d73faef3fb7e1d08041dddeefd |
| publicationDate |
2005-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2556593-A1 |
| titleOfInvention |
Silyl linker for solid-phase synthesis of nucleic acid |
| abstract |
A silyl linker that can be efficiently introduced in a solid-phase support for use in the synthesis of nucleic acid oligomers such as DNA. There is provided a silyl linker for solid-phase synthesis of nucleic acid, comprised of a compound of the general formula: H-(R1)Si(R2)-(C6H4)-CONH-(A)-COOH (I) (wherein each of R1 and R2 is an alkyl or aryl, and (A) represents a spacer moiety), or a salt thereof. There is further provided a 3~-end nucleoside unit having the above compound linked via an oxygen atom to the 3-position of sugar of nucleoside or a derivative thereof. There is still further provided a solid-phase support having the 3~-end nucleoside unit introduced therein, and provided a method of synthesizing a nucleic acid oligomer with the use of the solid-phase support. |
| priorityDate |
2004-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |