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filingDate 2005-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1feaf704ca997f95d142133605250b4
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publicationDate 2005-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2555684-A1
titleOfInvention Crystal structures and models for fc receptors and uses thereof in the design or identification of fc receptor modulator compounds
abstract The invention relates to the determination of the three-dimensional structures of Fc receptor proteins, particularly wild-type Fc.gamma.RIIa, by X-ray crystallography and the use of the structure in identifying and modifying agents for modulating the biological activity of Fc receptors. Also disclosed is a novel dimeric structure for Fc.gamma.RIIa and novel target sites for agents for modulating the biological activity of Fc receptor proteins.
priorityDate 2004-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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