| abstract |
A urea derivative or a salt thereof which each is useful as a therapeutic agent for thrombosis. The derivative is represented by the formula (I) [Chemical formula 1] wherein Cy represents an optionally substituted aromatic hydrocarbon group or optionally substituted aromatic heterocyclic group; R1 represents hydrogen or an optionally substituted hydrocarbon group; V represents -C(O)-, -S(O)-, or -S(O)2-; W represents -N(R2)-, -O-, or a bond (R2 represents hydrogen or an optionally substituted hydrocarbon group); X represents optionally substituted alkylene; Y represents -C(O)-, -S(O)-, or -S(O)2-; Z represents a bond, an optionally substituted chain hydrocarbon group, or -N=; ring A represents an optionally substituted nonaromatic nitrogenous heterocycle; ring B represents an optionally substituted nitrogenous heterocycle; and [Chemical formula 2] each independently indicates a single bond or double bond; provided that R1 may be bonded to R2 to form an optionally substituted nonaromatic nitrogenous heterocycle and that R2 may be bonded to a substituent of X to form an optionally substituted nonaromatic nitrogenous heterocycle. |