Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f600d1296c13d2e86af0e53efe367729 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
filingDate |
2004-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d5fc15ed0e6f7497be834b3ac09388d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b70c3df657b23d3c4d62bd3038374ed1 |
publicationDate |
2005-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2546401-A1 |
titleOfInvention |
The methods for screening using ctgf and trka receptor for the identification of compounds for use in treatment of fibrosis |
abstract |
The invention provides a method for identifying and/or making compounds for use in reducing and/or preventing fibrosis, comprising the steps: providing a CTGF receptor; providing a test sample; providing a CTGF receptor agonist; exposing the CTGF receptor to the test sample; subsequently or simultaneously exposing the CTGF receptor to the CTGF receptor agonist; detecting and/or measuring the amount of CTGF receptor activation; comparing the amount of CTGF receptor activation detected and/or measured in the presence of the test sample with the amount of CTGF receptor activation detected and/or measured in the absence of a test sample; determining if a compound reduces and/or prevents fibrosis on the basis that it causes no increase or a decrease in CTGF receptor activation. There is also provided compounds for reducing and/or preventing fibrosis and uses of such compounds. |
priorityDate |
2003-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |