| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2004-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86ab0b4473fe7b9018f14dc81b3664a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0742812feb24bb69a9d098b5b584bc31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4288026cdc81f952da6b227a6f2d51a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ea8001268feb2d2835d7175f43ad31a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70f35b5746b086f97219d106cec663c1 |
| publicationDate |
2005-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2545722-A1 |
| titleOfInvention |
Methods of treating asthma |
| abstract |
Methods for agents useful for treating asthma are disclosed. The methods include screening for agents that inhibit the production of a PKC-.theta. protein, as well as for agents that inhibit the kinase activity of a PKC-.theta. protein, or a functional fragment thereof, wherein such agents are useful for treating asthma. The methods also include screening for agents that inhibit the production of a reporter gene product encoded by a nucleic acid sequence operably linked to a PKC-.theta. promoter. Also disclosed are methods of treating asthma that include administering an agent that inhibits the production of a functional PKC-.theta. protein or the kinase activity of a PKC-.theta. protein or a functional fragment thereof. An isolated mast cell lacking expression of endogenous PKC-.theta. is also disclosed. |
| priorityDate |
2003-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |