http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2545171-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 2004-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b8ecf88d3cf27ef4c662207973d1223 |
| publicationDate | 2005-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2545171-A1 |
| titleOfInvention | Screening method with the use of tbk1 knockout mouse |
| abstract | It is intended to a method of screening a substance promoting the induction of an antiviral protein (for example, IFN-.beta.) against LPS stimulation or viral infection by using a TBK1 knockout mouse or a tissue or a cell originating in this knockout mouse. A promoter for a response to LPS stimulation or viral infection is screened by using a mouse, which has a defect in a TANK-binding kinase 1 (TBK1) gene, either as a whole or a part thereof, on chromosome and lacks a function of expressing TBK1 expressed in the wild type, or a tissue or a cell originating in the mouse together with a test substance and a ligand recognized by TLR4 or a material containing the same, and measuring and evaluating the extent of inducing an antiviral protein such as IFN-.beta. against the ligand recognized by TLR4 or a material containing the same in the above-described mouse or a tissue or a cell originating in the mouse. |
| priorityDate | 2003-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 589.