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filingDate 2004-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72b4416f47c3d6d26e559211057c11eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1af989b8faf1e9125ad1169790e93f8
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publicationDate 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2545139-C
titleOfInvention Low-dose tablets having a network of polymers
abstract The present invention relates to low dose tablets obtained by direct compression of microgranules which consist essentially of a neutral support, covered with a polymeric layer comprising at least one pharmaceutically acceptable polymer and allowing the modified release of active ingredients in an aqueous medium, on which a layer is applied active compound comprising at least one active ingredient. Tablets according to the invention advantageously have a matrix effect similar to that obtained with conventional matrix tablets, which depends on the nature of the polymers used for the constitution of the polymeric layer. This matrix effect allows modulation of the release profile of the principle active transported according to the type of polymer used. Such tablets are particularly conducive to the production of low dose tablets. The present invention furthermore relates to the process for producing these tablets and their use, in particular for the administration of active ingredients weakly to very weakly dosed.
priorityDate 2003-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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