| abstract |
The invention relates to the use of a peptide of general formula (I), wherein R1 and R2 are identical or different and represent hydrogen, a saturated or unsaturated hydrocarbon radical with 1 10, particularly 1 -3 hydrocarbon atoms, Z1 represents a histidine or proline radical, Z2 represents an arginine radical, a peptide radical or a protein radical with an arginine radical at the beginning of the chain, particularly with 2 -30 amino acids, said peptide possessing the biological property of matching the inducible VE-cadherin binding motive on the B~-chain (i.e. B~15-42) of human fibrin, for the production of a pharmaceutical preparation used to treat shock. |