Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fc6c2e9e63b6561f2f46b1de31f6379 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-006 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
filingDate |
2004-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3810a824055eb97a274f8d6881776f96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6931532e351b1980bf2f2264cbffe8f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01c922393df81adec4be1baacc28aa4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d97cf7e37a6ff0477a2f028628c568e6 |
publicationDate |
2005-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2529509-A1 |
titleOfInvention |
Methods for the stereoselective synthesis and enantiomeric enrichment of .beta.-amino acids |
abstract |
The present invention relates to methods for the stereospecific synthesis and for the enantiomeric enrichment of Beta-amino acids. A novel D-Beta-aminotransferase, which exhibits stereoselectivity for D-Beta phenyalanine D-3-amino-3-phenylpropanoic acid, was purified from a newly-isolated strain of Variovorax paradoxus. A novel L-Beta- aminotransferase was purified from a newly-isolated strain of Alcaligenes eutrophus. The D- and L-Beta-aminotransferases can be used to facilitate the stereoselective biosynthesis of Beta-D-phenylalanine or Beta-L-phenylalanine, from a mixture of L-glutamic acid or L-alanine, respectively, and 3-keto-3-phenypropanoic acid in the presence of the cofactor pyridoxal photephate. |
priorityDate |
2003-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |