| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbdc68ca0aa38fef2d059853ef2b31e6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B29C48-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B29C48-33 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C48-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C48-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C48-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 |
| filingDate |
2004-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_855e91f761e7c57c88fc8dc7dd8c5780
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1022e980082aafc2e8f6f8e462ab7e90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d089245483e5128f507e3e4f3c29f83c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4a3a72704b472bf1bca19abaae9f12f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0af3f6d182dab53513525872a5a9f62b |
| publicationDate |
2005-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2528134-A1 |
| titleOfInvention |
Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof |
| abstract |
A tubular tissue scaffold is described which comprises a tube having a wall, wherein the wall includes biopolymer fibrils that are aligned in a helical pattern around the longitudinal axis of the tube where the pitch of the helical pattern changes with the radial position in the tube wall. The scaffold is capable of directing the morphological pattern of attached and growing cells to form a helical pattern around the tube walls. Additionally, an apparatus for producing such a tubular tissue scaffold is disclosed, the apparatus comprising a biopolymer gel dispersion feed pump that is operably connected to a tube-forming device having an exit port, where the tube-forming device is capable of producing a tube from the gel dispersion while providing an angular shear force across the wall of the tube, and a liquid bath located to receive the tubular tissue scaffold from the tube-forming device. A method for producing the tubular tissue scaffolds is also disclosed. Also, artificial tissue comprising living cells attached to a tubular tissue scaffold as described herein is disclosed. Methods for using the artificial tissue are also disclosed. |
| priorityDate |
2003-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |