| abstract |
A cyanofluoropyrrolidine compound represented by the following formula (I): (wherein A represents hydrogen or fluorine; R1 and R2 are the same as defined in the description; X represents a single bond or C1-3 alkylene; and R3 represents -N(R4)COR5, -N(R4)SO2R5, etc.), a pharmaceutically acceptable salt of the compound, or a hydrate of the compound. They are useful as a preventive or therapeutic agent for diseases or states which can be alleviated by inhibiting dipeptydyl peptidase IV (DPPIV) and for diabetes, immunologic diseases, etc. |