http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2524572-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efb35e154fff5d3177ae8520d41046d5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B- |
| filingDate | 2004-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b5ce7a6866c4761f940e3ad91208e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bf21c5b3bc1857efb375592ef581ca3 |
| publicationDate | 2004-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2524572-A1 |
| titleOfInvention | Oligonucleotides comprising a molecular switch having enhanced sensitivity to the presence of a mismatch |
| abstract | This invention relates to oligonucleotides comprising a molecular switch whi ch may exist in an "open" or "closed" position. The molecular switch portion of the probe is particularly sensitive to the identity of sequences complementa ry to the molecular switch. Oligonucleotides containing a molecular switch are applicable to all kinds of hybridization processes. Due to the sensitivity o f the switch domain of the oligonucleotide, probes containing a molecular swit ch are particularly useful in the identification of single point mismatches. Mo re specifically, a portion, but not all, of the oligonucleotide becomes unbound from a mismatched target. The invention further relates to methods of using said oligonucleotides for research reagents, and clinical diagnostics. An exemplary oligonucleotide comprises a first hybridizable domain, a second bridging block domain, and a third binding domain. |
| priorityDate | 2003-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 182.