http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2523745-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-58 |
filingDate | 2005-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9927f8fb050bbcfd9a12255d9afdbe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9501fb786c1a16894a29ae6770d7211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c39f4927b1f503ab7d279c3c340b33ab |
publicationDate | 2011-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2523745-C |
titleOfInvention | High-throughput prion assays |
abstract | The invention is directed to a method for performing a high-throughput test to determine the presence of PrPsc in a tissue sample taken post mortem from brain, comprising: (A) sample preparation, (B) sample treatment, (C) sample analysis, (D) controls, and (E) classifying the results of the analysis. The invention is further directed to preparing a treated biological sample suspected of containing PrPsc suitable for detection of PrPsc. The method comprises (a) homogenizing the sample; (b) digesting the sample proteolytically by adding to the homogenate Proteinase K and incubating the sample; (c) adding a peptidic protease inhibitor to the incubated mixture of step (b). The invention further provides a conditioned microwell plate, and a soluble fusion protein. |
priorityDate | 2004-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 327.