| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eefa48f9b21fc8e5b5ceb014f4581255 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64 |
| filingDate |
2004-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e194285c976573dd8db6ffa32e017ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e76b0a2c38126af0998b6cd1b57587e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_917d392cee8728d359ec7fa073d0f12f |
| publicationDate |
2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2521116-A1 |
| titleOfInvention |
Process for preparation of cyclosporin "a" analogues having a terminal diene group |
| abstract |
The invention is concerned with a new process for the preparation of a cyclosporin A analog of formula I comprising, a) allylating a protected cyclosporin A aldehyde with a allylmetal reagent and, b) converting the compound obtained in step a) to the cyclosporin A analog of formula I. In particular, the allyl reagent is a trimethylsilyl-allyl borate ester or a trimethylsilyl-allyl organometallic compound containing aluminium or titanium. |
| priorityDate |
2003-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |