| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0881f427030de6a3dc5579ee18c8145f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2004-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f288a4fa21362394274ea4a4ecb3976e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b017f124bea9098be09bbfbfd2f998fe |
| publicationDate |
2004-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2519826-A1 |
| titleOfInvention |
Cell death-inducing fusion gene specifically acting on cancer and product thereof |
| abstract |
It is intended to provide a protein having a potent effect of inducing cell death (i.e., a fused protein having a denatured Bax protein carrying GEP fused to the N-terminal and a homing signal peptide having a homing effect on cancer cells further fused in the N-terminal side); a gene encoding the fused protein; and a cancer cell proliferation inhibitor containing the fused protein. Namely, a fused gene containing a cell death-inducing gene specifically acting on cancer cells, which is a fused gene having a gene encoding a cancer cell-specific homing signal peptide sequence, a gene encoding a green fluorescent protein (GFP) and a gene encoding .DELTA.-NBax with a deletion of the N-terminal sequence containing BH3 region of human Bax in this order, and a fused protein encoded by the fused gene. |
| priorityDate |
2003-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |