http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2519696-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e29526f284c0155fd79806c9dd5a1c7 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-065 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B- |
filingDate | 2004-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddb65069d95fc62e0c049b33f83c2872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7bca7b111e86b88a98b7350a1a60aca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_304bef5edf103aff4686cdb86b6d6e91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_608c9164c5414f65d34386f23a0d90e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdba71648c4fdfff213cae5f32bf2085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c3174634910489c03bb1dfcfa6e411 |
publicationDate | 2004-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2519696-A1 |
titleOfInvention | Methods of assessing crohn's disease patient phenotype by i2, ompc and asca serologic response |
abstract | The invention provides a method of diagnosing or predicting susceptibility to a clinical subtype of Crohn's disease in a subject having Crohn's disease by determining the presence or absence of IgA anti-I2 antibodies in the subject, where the presence of the IgA anti-I2 antibodies indicates that the subject has a clinical subtype of Crohn's disease. In one embodiment, a method of the invention is practiced by further determining the presence or absence in the subject of a NOD2 variant, anti-Saccharomyces cerevisiae antibodies (ASCA), IgA anti-OmpC antibodies, or perinuclear anti-neutrophil cytoplasmic antibodies (pANCA). The methods of the invention can be used to diagnose or predict susceptibility to a clinical subtype of Crohn's disease, for example, a fibrostenotic subtype, a subtype characterized by the need for small bowel surgery, or a subtype characterized by the absence of features of ulcerative colitis. |
priorityDate | 2003-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 428.