| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fdaffe64e0056ceff97698a913ed913 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate |
2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf2e03d6c1ee8e7c83158bed598aa5af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b023e23a2e1f987bb1fa8aa95c44c0a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8e7f945203c29f1765a3a065912c00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea2917caee4efc8e2d338ef40432d3fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4ab8b4291b166b2504cde777263f419 |
| publicationDate |
2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2519414-A1 |
| titleOfInvention |
Methods of treating inflammatory diseases associated with bone destruction |
| abstract |
A method of treating an inflammatory disease associated with bone destruction which comprises the step of administering a virus vector having a gene inhibiting the signal transduction mediated by fibroblast growth factor 2 (FGF2)-FGF receptor 1-Ras-Raf-MAP kinase to the affected site. A composition for treating an inflammatory disease associated with bone destruction which contains the above vector. By inhibiting the FGF2 signal transduction by topically administering the virus vector, inflammation and bone destruction in inflammatory bone destruction can be successfully suppressed at the same time. Thus, a method of specifically and effectively treating inflammatory bone diseases such as rheumatoid arthritis, which can be hardly treated hitherto, and a composition for treating the same are provided. |
| priorityDate |
2003-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |