Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fb2e4f7d6fa466e4dc5f97c5e60a4d7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2004-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec24926c2162f2f1793e9c53206aa46b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_850baa2ae89d426ca107cf8507ff29dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2ee156ad76c893bcc4a7c9720683da4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad3fbe20ac352c4685bdecb9bf8027ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0108a62adee3834959c0c95d1456c1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e91744cf2020957c32a7fd57a815d33 |
publicationDate |
2004-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2519131-A1 |
titleOfInvention |
Ligands for tgf-beta binding proteins and uses thereof |
abstract |
Compositions and methods are provided that relate to the unexpected specific association of (i) the TGF-beta binding protein sclerostin with the BMP antagonist protein chordin to form a complex, and of (ii) the TGF-beta binding protein sclerostin with the BMP antagonist protein noggin to form a complex, either of which complex is incapable of binding to a TGF-beta superfamily member such as a BMP. The invention provides isolated complexes for use in screening assays to identify agents that modulate bone mineralization, and offers other related advantages. |
priorityDate |
2003-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |